Researchers at Osaka Metropolitan University have developed a new method to accurately measure kidney function, particularly to detect hyperfiltration, a common kidney disorder.. This innovation was a response to the problems of diagnosing diabetic nephropathy in older people, in whom an age-related decrease in glomerular filtration rate (GFR) hides early signs of organ disease, writes Osaka Metropolitan University.
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A team led by Dr. Akihiro Tsuda analyzed data from 180 kidney transplant candidates. Their results showed that the traditional approach of adjusting GFR measurements for body surface area does not work in obese patients, masking signs of hyperfiltration. Instead, they proposed a formula that directly takes into account age-related changes in GFR, offering a more accurate diagnostic tool.
Dr. Tsuda highlighted the potential of the new method for the early detection and treatment of diabetic nephropathy, saying: "
In diabetic nephropathy, early detection of albuminuria, characterized by excess albumin in the urine, is critical as it often precedes a decrease in GFR. The study, published in the journal Hypertension Research, suggests the need to improve traditional diagnostic methods, especially in populations with naturally decreased GFR, such as older adults.
The importance of this study is due to the increasing prevalence of diabetes worldwide. As of 2021, about 537 million adults aged 20-79 suffered from diabetes, and scientists predict that this number will rise to 643 million by 2030.
Kidney disease is a major complication of diabetes, so improving diagnostic methods is vital to public health. The new formula developed by Dr. Tsuda's team may lead to improved patient outcomes through earlier detection of disease progression and timely intervention..
Focus previously wrote that humanity will be overwhelmed by a wave of diabetes by 2050. From millions to billions: new study reveals grim prospects for diabetes worldwide by 2050 unless health systems act proactively.
Focus also wrote that diabetes affects brain damage. Recent studies have shown that patients with type 1 diabetes experience early brain aging.
Important! This article is based on and does not contradict the latest scientific and medical research. The text is for informational purposes only and does not contain medical advice.. To establish a diagnosis, be sure to consult a doctor.