Dutch scientists working at the Radboud University in Nijmengen decided to investigate the connection that a protein deficiency has with the ability of the brain. It turns out that the lack of this substance leads to mental disorders..
Scientists from the Netherlands also found that both of these deviations are caused by the same gene mutation. Mutation of genes in the child, and not in his parents, leads to mental disorders. The consequence of such a mutation is that cells lose their ability to produce functional proteins.. This is what leads to the fact that ailments begin to develop in the human brain..
To understand exactly how this works, a team of scientists led by geneticist Christian Gillissen used data not only on those with intellectual disabilities in the Netherlands, but also an international database..
In the course of the research, fifteen genes were found, the mutations of which are closely related. What happens to twelve of them, and leads to violations in the development of the brain.
Mutations affect the tiny fraction of a protein that continues to function, scientists say.. The problem, as the experts found, is that this process covers the surface of the protein, which disrupts its interaction with others like itself and causes further problems with the brain..
aspect. net.