People who work or rise in price at night often have problems with the intestines.

Studies from the Portuguese Science Foundation of Champalimo have shown that the functioning of a group of immune cells, which give a significant impact on a healthy intestine, lie in a biological biological year for the body. A report on this topic was published in the journal Nature, inform Ukr. media.

“Deprivation or disruption of the sonorous nature of sleep can cause serious consequences for health and provoke a number of illnesses, which often cause an immune component, for example, inflammation of the intestines,” says Enrique Veiga-Fernandez, a researcher of the previous group. “In order to understand why you need to know, we lied about nutrition, to add circadian rhythms to the immune cells of the intestine”.

May all cells of the human body develop an internal genetic mechanism of synchronization with circadian rhythms - through the expression of the so-called " This mechanism informs the client about an hour to achieve and help them to work in a coordinated way, ensuring the normal functioning of the whole organism.

“Clitains in our style do not allow direct access to information about the city’s lighting, for which the clergy can be remembered,” explains Veiga-Fernandez. — Brain anniversaries, as they can provide direct information about the day of light, it’s up to you to create all these anniversaries in the middle of the body in such a way as to synchronize all the systems and secure our well-being”.

In the process of cultivation, the interrelationship of the immune system and circadian rhythms of the veins gave way to ILC3-cells, which turned out to be the most responsive to the destruction of the robotic genes of the year. ILC3 is one of a variety of congenital immune cells. They play an important role in tissue homeostasis and take part in a swedish cytokine-depleted response organism under the hour of ignition processes.

“Specifically, congenital cells of the third type,” explains Veiga-Fernandez, “are responsible for the integrity of the intestinal epithelium and control the absorption of lipids. If we disrupted the work of the clitin's birthday, then they showed that the number of ILC3 in the intestine significantly changed. This led to severe inflammation, destruction of the intestinal barrier and overworld accumulation of fats "

As it was stated, the key problem is in the damaged expression of the ARNTL gene. It has long been known that protein, which is encoded by the cym gene, plays an important role in the formation of circadian rhythms: mice with knockouts (in the distance or in the absence).

As it turned out, for the ILC3 ARNTL-protein I have a similar function. It regulates the expression of specific proteins on the membranes of these lymphocytes, which are called “clitin postal codes”. Qi "

“Before the hour of the day's sleeplessness, if in fact, the biological year of the brain decreases the activity of ILC3, in order to accept healthy lipid metabolism. After the end of the intake of ILC3, it will be possible to stop the infusion from turning into the intestines, de stinks are needed to fight against foreign microflora and regeneration of the epithelium, ”Veiga-Fernandez suggested. In people who work at night, the whole process of moving lymphocytes is disrupted, which leads to dysfunction and bowel disease.

aspect. net.