Healthy Gut Microbiota May Prevent Metabolic Syndrome. This is stated by researchers from the University of Georgia in the pages of the journal Gastroenterology..

Metabolic syndrome is a combination of risk factors associated with heart disease, diabetes, and stroke.. It is characterized by high levels of triglycerides and low-density lipoprotein (LDL) in the blood, elevated fasting glucose levels and a large waist circumference, according to Pannochka, an online publication for girls and women aged 14 to 35.. net According to the US National Institutes of Health, people with metabolic syndrome are 2 times more likely to develop heart failure and 5 times more likely to develop type 2 diabetes than the general population.

The American Heart Association (ANA) reports that about 34% of American adults have metabolic syndrome, with it becoming a more common problem every year.. This forces scientists to actively look for the causes of the syndrome and new, sometimes non-standard methods of dealing with it..

A team of researchers from Georgia State University in Atlanta and Cornell University in Ithaca found that disrupted gut microflora plays a role in the development of metabolic syndrome..

The disruption of the microflora contributes to increased levels of inflammation in the intestines, and also increases the risk of developing chronic inflammatory bowel diseases, such as Crohn's disease or ulcerative colitis..

A new study helped scientists explain the essence of this phenomenon. According to one of the authors, Dr. Andrew Gewirtz, professor at the Institute of Biomedical Sciences at Georgia State, the latest work has revealed the mechanisms of influence of microflora on metabolic syndrome..

He writes: “All this loss of TLR5 in the intestinal epithelium. The cells that line the surface of the intestine are able to respond to the presence of " This ability is lost if the gut becomes colonized by a more aggressive microbial population.. They produce substances that cause inflammation and cell death.”.

In an animal model (lab mice from the same litter), researchers have shown that gut bacterial species that cause inflammation are much more aggressive than other gut microbes.. Some mice were missing the TLR5 gene, which is associated with the flourishing of pathogenic microflora that causes metabolic syndrome.

Dr. Ruth Ley, of the Department of Microbiology and Molecular Biology at Cornell University, explains: “These results validate our concept. Normalization of the gut microflora can treat and prevent metabolic syndrome. Abnormal composition of the microflora contributes to the maintenance of mild chronic inflammation in the intestine and the development of metabolic syndrome, and possibly other diseases.. We have demonstrated that the pathogenic microflora is more aggressive and produces a large amount of harmful substances, such as flagellin and lipopolysaccharide."

Metabolic syndrome and diet.

And in the end, a few words about other achievements in the study of metabolic syndrome. Recently, scientists reported that a Mediterranean diet rich in nuts and olive oil could reverse metabolic syndrome..

The authors of this study had a group of people eat a regular low-fat diet, a Mediterranean diet with nuts, or a Mediterranean diet with extra olive oil.. Follow-up lasted an average of 4.8 years.

Participants who ate the modified Mediterranean diet (the last two options) showed significant reductions in blood glucose levels. In addition, the percentage of abdominal obesity decreased in these groups.. At the start of the study, 64% of participants had metabolic syndrome. By the end of the study, 28.2% of those participants who were on a Mediterranean diet no longer met the criteria for metabolic syndrome..

medbe. en.