The researchers were able to generate cells under laboratory conditions that meet the requirements of the gold standard of the pharmaceutical industry when testing drug safety.

Generation of liver cells.

Scientists have used stem cell technology to generate liver cells that help the body take drugs. They found that the cells obtained are as effective as the human liver cells of the living liver, currently used to assess the safety of drugs.

The problem is that the cells of living liver tissue are deficient and vary significantly among different donors. So it is impossible to name the ideal assistant when creating medicines.. Stem cell technology developed in Edinburgh addresses these problems by offering reproducible unified liver cells in the laboratory. ".

"Various genetic information plays a key role in the treatment of medicines in the patient's liver. Now we are able to effectively reproduce human liver cells in the laboratory from different people who will model their functional genetic differences, "says Dr. David Hay from the Medical Research Center at the University of Regenerative Medicine.

Scientists hope to produce liver cells containing different DNAs that reflect genetic variations in the metabolism of the human population. They can be used to detect differences in the reactions of patients' organisms to drugs.

Also, cells produced in the laboratory can be used to closely monitor the effects of drugs in order to optimize the patient's treatment process.

In the future, researchers intend to create a company for the commercial use of the results of their work. Her results are published in the Journal of Transnational Stem Cell Medicine (Stem Cells Translational Medicine).

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