At the Institute of Nutrition (Germany), a new gene was found associated with diabetes, whose mechanism is able to reduce the risk of disease with obesity.
A fragment of the genome found in some mice reduces the activity of the Zfp69 gene, whose work is enhanced in fat people with diabetes.
In the world, about 1.6 billion people are overweight, and the number of patients with diabetes has reached 230 million. At 50%, the risk of developing type 2 diabetes is due to hereditary factors, but lifestyle and nutrition are important.
Scientists compared the genomes of mice, paying attention to those who, despite obesity, glucose levels did not increase.
Thus, they calculated a "hopping gene" or "transposon" of viral origin, localized in the Zfp69 gene segment, which saved animals from metabolic disorders. It is this genetic fragment that reduced the risk of developing diabetes.
Scientists have suggested that the protein produced by the gene increases the size of fat cells, leading to its deposition in the liver and diabetes.
The new gene is also characteristic of humans, and with high activity it is able to disable the work of the gene Zfp69, which causes diabetes health. Sumy. Ua.
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