Genetics followed the activity of genes in the body of men and women and came to the conclusion that the work of 6,500 of them is different.
According to the researchers, both men and women have virtually the same DNA, except for a small "male" Y chromosome, which is present only in men and contains a relatively small number of "working" genes. Recent experiments in mice show that a full-fledged male organism can be grown without it, having transferred only two genes from the Y-chromosome to another part of the genome. At the same time, the work of the male and female body is very different.
During the study, scientists took samples of blood and body tissues from 550 men and women, decoded their DNA and analyzed which genes were active in different cells of their body.
It turned out that about a quarter of the well-known scientist's set of DNA sections coding for proteins worked quite differently in the body of men and women.
About six thousand genes were associated with the work of just one type of tissue - breasts and mammary glands. Most of the other genes were also associated with the work of one organ, and only three dozen genes influenced the work of six or more tissues. Interestingly, some genes located on the female X chromosome are much more active in men than women. Unambiguous explanation for this yet.
Differences in the work of about a hundred genes associated with the heart, blood vessels, fatty tissue and other vital organs, can explain, as scientists believe, the difference in predisposition to diseases. For example, the gene NPPB, responsible for protecting the heart from heart attacks and the circulation of calcium, was particularly active in the body of young girls, but sharply reduced its activity at the onset of menopause. This behavior of this part of the DNA will explain why women aged more often suffer from osteoporosis and heart problems.
Earlier it was reported that scientists conducted a study, the results of which helped them discover a group of genes, the removal of which leads to a sharp increase in life expectancy. Scientists hope in the future to create drugs that will suppress the work of some genes and thus prolong life.